Orlistat is significantly used to treat obesity. It indicated to lessen the danger for weight restore after prior weight reduction.
XENICAL is indicated for weight problems management including weight reduction and weight maintenance when used along with a lower-calorie diet. It can also be indicated to lessen the danger for weight restore after prior weight reduction.
Advantages:
•It is the only prescribed “fat blocker”, whereas most other weight loss pills are merely appetite suppressants.
•if you are severely overweight, you may notice that your weight loss is more rapid.
•It has been clinically studied and has been found to bring positive results.
Disadvantages : With Xenical this might include frequent diarrhoea due to the body dispelling more fat.
Precautions:
•For patients receiving both XENICAL and cyclosporine therapy, administer cyclosporine 3 hours after this drug.
•For patients receiving both XENICAL and levothyroxine therapy, administer levothyroxine and XENICAL at least 4 hours apart. Patients treated concomitantly with XENICAL and levothyroxine should be monitored for changes in thyroid function.
Side effects:
•oily Noticing inside the undergarments,
•oily or fatty stools, orange or brown colored oil inside your stool
•gas with discharge, an oily discharge,
•loose stools, or perhaps an urgent have to use the bathroom, lack of ability to manage bowel movement.
•stomach discomfort, nausea, vomiting, diarrhea, rectal discomfort or
•weakness, dark urine, clay-colored stools, itchiness, appetite loss, or jaundice (yellowing of your skin or eyes).
Contraindications:
It is contraindicated during pregnancy, because weight loss offers no potential benefit to a pregnant woman and may result in fetal harm. A minimum weight gain, and no weight loss, is currently recommended for all pregnant women, including those who are already overweight or obese, due to the .If this drug is used during pregnancy, or if the patient becomes pregnant while taking this drug, the patient should be apprised of the potential hazard of maternal weight loss to the fetus.
Drug interactions:
•Cyclosporine
This drug and cyclosporine drug interaction indicate a reduction in cyclosporine plasma levels when Xenical was coadministered with cyclosporine. Xenical and cyclosporine should not be simultaneously coadministered. Cyclosporine should be administered 3 hours after the administration of this drug.
•Fat-soluble Vitamin Supplements and Analogues
•Pharmacokinetic interaction study showed that the absorption of beta-carotene supplement is reduced when concomitantly administered with this product. Xenical inhibited absorption of a vitamin E acetate supplement. The effect of this on the absorption of supplemental vitamin D, vitamin A, and nutritionally-derived vitamin K is not known at this time.
•Levothyroxine Hypothyroidism has been reported in patients treated concomitantly with Xenical and levothyroxine postmarketing .Patients treated concomitantly with this drug and levothyroxine should be monitored for changes in thyroid function. Administer levothyroxine and Xenical at least 4 hours apart .
•Warfarin
•Vitamin K absorption may be decreased withthis medicine. Patients on chronic stable doses of warfarin who are prescribed this drug should be monitored closely for changes in coagulation parameters
Dosage : The suggested dose of XENICAL is a 120-mg capsule three times each day with every primary meal that contains body fat (throughout or as much as one hour following the meal).
Storage : Store at room temperature at 25 0C away from light and moisture.
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