Your Guide to Jakafi for Polycythemia Vera: What You Need Know

## Jakafi for Polycythemia Vera

Jakafi (ruxolitinib) is a prescription medicine approved by the US Food and Drug Administration (FDA) to treat polycythemia vera (PV) in adults who are resistant to or intolerant of hydroxyurea.

PV is a rare type of blood cancer that causes the body to make too many red blood cells, which can lead to problems such as blood clots, stroke, and heart failure. Jakafi works by blocking the action of a protein called JAK2, which is involved in the growth and spread of PV cells.

How to Take Jakafi

Jakafi is taken orally, in tablet form. The usual starting dose is 10 mg twice a day. Your doctor may increase or decrease your dose based on how well you respond to treatment and how well you tolerate the medicine.

Side Effects of Jakafi

The most common side effects of Jakafi include:

* Anemia

* Fatigue

* Nausea

* Vomiting

* Diarrhea

* Constipation

* Headache

* Dizziness

* Bruising

* Nosebleeds

* Skin rash

* Itching

These side effects are usually mild and go away within a few weeks of starting treatment. However, some side effects can be more serious, such as:

* Infection

* Liver damage

* Kidney damage

* Heart problems

* Lung problems

* Stroke

Talk to your doctor about any side effects that bother you or do not go away.

Warnings and Precautions

Jakafi can cause birth defects if taken during pregnancy. Women who are pregnant or plan to become pregnant should not take Jakafi.

Jakafi can interact with other medicines, including blood thinners, anticoagulants, and certain antibiotics. Tell your doctor about all the medicines you are taking, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

How to Manage Side Effects of Jakafi

Here are some tips to help manage side effects of Jakafi:

* Talk to your doctor: Tell your doctor about any side effects that you experience. Your doctor can recommend ways to manage your side effects and help you feel better.

* Stay hydrated: Drink plenty of fluids to help prevent dehydration, which can worsen some of the side effects of Jakafi.

* Eat a healthy diet: Eat a healthy diet to help maintain your strength and energy levels.

* Get regular exercise: Get regular exercise to help improve your overall health and well-being.

* Avoid alcohol and tobacco: Avoid alcohol and tobacco to help reduce your risk of side effects.

Conclusion

Jakafi is a safe and effective treatment for polycythemia vera. It is important to talk to your doctor about the risks and benefits of Jakafi to decide if it is right for you.

Cheese: Are There Health Benefits? a Ketogenic Diet?