QuestionWHAT DISEASE DOES OCCURE IN THE DIFFECIENCY OF CHOLESTROL?
AnswerAqeel Kahn,
There are several articles that will answer your question. I will point you to those articles and ask that you read them yourself. I cannot explain the disease and syndrome here -it would take too much space and be too complicated.
Smith-Lemli-Opitz syndrome (SLOS)
http://www.emedicine.com/ped/topic2117.htm
A cholesterol deficiency syndrome in humans.
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=295355
Cholesterol deficiency increases the vulnerability of hippocampal glia in primary culture to glutamate-induced excitotoxicity.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=1...
Abnormal sterols in cholesterol-deficiency diseases cause secretory granule malformation and decreased membrane curvature
http://jcs.biologists.org/cgi/content/full/119/9/1876
You can find other articles if you do a search for "cholesterol deficiency" or "Smith-Lemli-Opitz syndrome".
I hope this helps.
Todd
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