Lose Weight > Question and Answer > About Weight Loss > Can losing a lot of weight affect your menstrual cycle?
Can losing a lot of weight affect your menstrual cycle?
Can losing a lot of weight affect your menstrual cycle?
Basic cholesterol compounds in fat cells can get changed into a type of weak estrogen called estrone. Overweight or obese women carrying extra fat cells have "little estrone-making factories, which have an estrogenic effect on glands," explains Maria Arias, MD, a gynecologist at Atlanta Women's Specialists in Georgia.A woman may go months without ovulating, for example, but the uterine lining is still accumulating - to the point that it becomes unstable.
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