Weight Reduction With 7-Keto DHEA

      According to Henry Lardy, PhD, of the National Academy of Sciences, 7-KETO DHEA offers the potential benefits of DHEA without the risks. 7-KETO DHEA is a natural metabolite, also called conversion product, of DHEA. After DHEA is converted to the 7-KETO form it can no longer be converted into a form used to make the sex hormones that increase cancer risks.
In preliminary studies on animals, 7-Keto DHEA stimulates the immune system, prevents muscle loss ,reduces stress, increases the calorie-burning rate by activating thermogenic liver enzymes and improves memory more than DHEA or a placebo. We will show you how 7-Keto DHEA can be used to help with another way to lose weight.
7-Keto DHEA is a metabolite of DHEA. It is a steroidal hormone that was originally discovered in the 1950s was not researched until the 1990s. Henry Lardy and his colleagues at the University of Wisconsin are studying this and related compounds for use in weight reduction, memory enhancement, immune system improvement, and skin integrity improvement.
The term 7-Keto DHEA is the brand name for the chemical compound 3-acetyl-7-oxo-dehydroepiandros-terone, a naturally occurring metabolite primarily produced in the adrenal glands and skin . It was first discovered in 1958, when it was found in urine.
Human blood levels of 7-Keto follow the same course over time as those of DHEA, rising until about the age 20 and then slowly descending beginning around the age of 30~Blood levels of 7-Keto follow the same course over time as DHEA, rising until about the age twenty and then slowly descends beginning around the age of thirty. Urinalysis shows that average blood concentrations of 7-Keto decline nearly 50% by age fifty.
This reduction in 7-Keto levels is partly causitive of the increases in body fat and total body weight frequently seen in older individuals," notes Dr. Sergey Dzugan, president of Life Extension Scientific Information, Inc. "This decline also plays a role in the compromised immune function that is a hallmark of the aging process. Moreover, since DHEA and 7-Keto DHEA decline at a more rapid rate than cortisol, this creates a period of cortisol dominance that can wreak havoc on the immune system. For these reasons, supplementation with 7-Keto is often recommended."
7-Keto DHEA produces fat reduction through the process of thermogenesis. This term refers to the creation of heat. Increased levels of ?thermogenesis ?causes the metabolic rate to be elevated, which results in the conversion of stored fat into energy.
7-Keto DHEA enhances the activity of three thermogenic enzymes that stimulate fatty acid oxidation in the liver. These thermogenic enhancing enzymes are fatty acyl CoA oxidase, malic enzyme, and glycerol-3-phosphate dehydrogenase.6,10-12. These enzymes cause the liver cells to burn fatty acids for energy, which causes a reduction of triglycerides in the liver.
Seven Keto DHEA supplementation has a dramatic effect on elevating levels of the thermogenic enhancing enzymes. ?A study published in Current Therapeutic Research revealed just how effective 7-Keto is in inducing rapid weight loss. In this randomized, double blind, placebo controlled study, thirty overweight adults were divided into two groups. Group 1 received 100 mg of 7-Keto twice daily for eight weeks, while group 2 took a matching placebo capsule. Subjects participated in an exercise program three times a week that consisted of one hour of aerobic and non-aerobic training under the supervision of an exercise physiologist. Additionally, each subject was instructed to follow an 1800-calorie per day diet. The subjects underwent testing for blood chemistry, body composition, blood pressure, and dietary analysis at baseline and at weeks four and eight.
Researchers found that the 7-Keto group lost a statistically significant amount of body weight in comparison to the placebo group. 6.3 versus 2.1 pounds. The 7-Keto group also lost a greater percentage of body fat compared to the placebo group. ?1.8% versus 0.57%. ? No adverse effects were reported. The results show that 7-Keto can significantly and safely reduce body weight and body fat when combined with exercise and a reduced-calorie diet. This is caused by increased levels of fat burning enzymes in the liver with the addition of thyroid hormone elevation. These changes are known to boost basal metabolic rate, making it easier to lose excess pounds. Supplementation with 7-Keto can therefore help reverse the decline in metabolic rate that makes it so easy to put on weight as we age. Different than caffeine and ephedrine, 7-Keto does not have a central nervous system stimulating effect, nor does 7-Keto increase heart rate or blood pressure.
Aging is associated with a decline in immune system response, with often-dramatic reductions in immune function~Aging is associated with a decline in immune system response. This leads to increased susceptibility to infections~This gives rise to increased susceptibility to infections. ?A study at the Minnesota Applied Research Center and the Geriatric Research Education and Clinical Center in Minneapolis found that four weeks of 7-Keto DHEA supplementation improved immune function in elderly men and women~?A clinical research study at the Minnesota Applied Research Center in Minneapolis Minnesota found that four weeks of 7-Keto DHEA supplementation improved immune function in elderly patients. ?In this randomized, double-blind, placebo-controlled study, 22 women and 20 men over the age of 65 took 100 mg of 7-Keto DHEA twice daily or a placebo of identical shape and size~In this randomized, double-blind, placebo controlled study, twenty two women and twenty men over the age of 65 took 100 mg of 7-Keto DHEA twice a day or a placebo. Patients in the 7-Keto group had a significant decrease in immune suppressor cells and a significant increase in immune helper cells~Patients in the 7-Keto group had a statistically significant decrease in immune suppressor cells and a significant increase in immune T-cell helper cells. Scientists came to the conclusion that 7-Keto was well tolerated and had no untoward effects.
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